Metaspray contains Mometasone Furoate, a corticosteroid with strong anti-inflammatory activity. Although the precise mechanism in allergic rhinitis is not fully understood, corticosteroids act on multiple cell types (mast cells, eosinophils, neutrophils, macrophages, lymphocytes) and mediators (histamine, eicosanoids, leukotrienes, cytokines) involved in inflammatory responses.
Metaspray nasal spray is used to treat nasal symptoms of allergic rhinitis in patients ≥2 years, prevent seasonal allergic rhinitis in those ≥12 years, and manage nasal polyps in adults ≥18 years.
Pediatric use: Safety and efficacy in children under 2 years are not established.
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Metaspray Nasal Spray is used to manage nasal symptoms associated with allergic rhinitis in patients aged 2 years and older. Its applications include:
Allergic Rhinitis:
Adults and children ≥12 years:
Standard dose: 2 sprays (50 mcg per spray) per nostril once daily (total 100 mcg/day)
For known seasonal allergens, prophylactic dosing may start 2–4 weeks before pollen season at 50 mcg per spray (200 mcg/day).
Children 2–11 years:
1 spray per nostril once daily (total 100 mcg/day)
Nasal Polyps (Adults ≥18 years):
Standard dose: 2 sprays per nostril twice daily (total 400 mcg/day)
Some patients may benefit from once daily dosing (total 200 mcg/day).
No significant drug interactions have been reported with Metaspray Nasal Spray.
Known hypersensitivity to Mometasone Furoate or any component of the spray.
Pregnancy Category C: Insufficient human studies; use only if benefits outweigh potential fetal risks.
Excretion in breast milk is unknown; exercise caution when administering to nursing mothers.
Store at or below 30°C, away from light and moisture.
Keep out of reach of children.
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